May help: CBT, Omega 3
The CRHR1 gene encodes a receptor for CRH, the first hormone of the HPA axis. Stress activates the HPA axis, resulting in cortisol release. Hence, CRH receptors play a significant role in stress response and related disorders [R, R].
CRH release causes fear and anxiety via the CRHR1 receptor [R, R].
People with PTSD tend to have excess CRH activity and dysfunctional HPA axis [R, R].
CRH activity via the CRHR1 receptor plays a crucial role in stress-related disorders such as PTSD