The HTR1B gene helps produce serotonin receptor.
The function of the 5-HT1B receptor differs depending upon its location (R). In the frontal cortex, it is believed to inhibit the release of dopamine (R).
In the basal ganglia and the striatum, serotonin inhibits the release of serotonin and decreases glutamate transmission (R). In the hippocampus, it produces a facilitation in excitatory synaptic transmission (R). Outside the brain, 5-HT1B receptor activation constricts the vessels in the lungs (which cause pulmonary hypertension and a higher heart rate) (R).
Can be associated with Raynauds
Attention disorders like ADHD and depression. To help with attention get more sleep, eat fish supplement with omega 3)
Chronic pain and headaches. To help try a little caffeine, or CBD oil. Acupunture may also help.