The SNP rs2736100 is part of the TERT gene, which codes for an enzyme called telomerase reverse transcriptase . This enzyme is involved in protecting telomeres, which are segments of DNA that prevent a cell’s genetic code from being altered or damaged during normal cell division [106] . Your genotype
(‘AC’; heterozygous) has been linked to a slightly increased likelihood of depression, suggesting that you may be at slightly elevated risk from this SNP [30, 10
Abnormal activity levels of the TERT gene may contribute to depressed moods by inhibiting theactivity of serotonin (5-HTR1a) receptors throughout the brain [107]. Reduced serotonin activity is oneof the main factors associated with low mood [108]. Therefore, you may be able to boost your mood and counteract your risk by increasing your brain’s levels of serotonin.