The CRHBP gene codes for corticotropin-releasing hormone-binding protein (CRH-BP). CRH-BP binds to corticotropin-releasing hormone (CRH) and blocks its actions. CRH plays a major role in the body’s stress response [R, R, R].
CRHBP variants have been linked to [R, R, R, R, R]:
- Antidepressant effectiveness
- Anxiety
- Substance abuse
- Schizophrenia
- IBS