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GRM8

May Help My Genetopye: L Theanine (Supplement or Tea)

The GRM8 gene codes for metabotropic glutamate receptor 8 (mGluR8). mGluR8 is activated by glutamate, a chemical that’s well known to excite the nervous system [R].

Interestingly, mGluR8 belongs to a group of glutamate receptors that lower nervous system activity when they’re activated [R].

mGluR8 plays many important roles. For example, it may influence [RR]:

  • Stress
  • Drug dependence
  • Gut function
  • Blood sugar levels
  • Weight

GRM8 variants are linked to [RRR]:

  • Higher stress 
  • Alcohol dependence
  • Schizophrenia
  • Depression